{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"digital::HIFU_PM","issue_slug":"digital","doc_id":"HIFU_PM","title":"High-Intensity Focused Ultrasound (HIFU) Efficacy, Safety, and Applications","doi":"10.62487/saimsarabe8c64ea","doi_url":"https://doi.org/10.62487/saimsarabe8c64ea","version":"2026-06-09","source_name":"PubMed","article_url":"https://saimsara.com/sessions/high-intensity-focused-ultrasound-20260531-101627-be8c64ea/","image_url":"","topic_tags":"High-intensity focused ultrasound,HIFU ablation,Thermal ablation,Focused ultrasound therapy,Prostate cancer,Uterine adenomyosis,Tumor immunotherapy,Sonothrombolysis,Venous insufficiency,Cosmetic rejuvenation","keywords":["High-intensity focused ultrasound","HIFU ablation","Thermal ablation","Focused ultrasound therapy","Prostate cancer","Uterine adenomyosis","Tumor immunotherapy","Sonothrombolysis","Venous insufficiency","Cosmetic rejuvenation"],"metrics":{"included_all":4333,"included_original":3163,"reference_index":740,"total_participants":288006},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=digital%3A%3AHIFU_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=digital%3A%3AHIFU_PM","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":92521,"preview":"Results Key finding aligned to the query: The central scoping-review finding is that HIFU functions less as a single disease-specific intervention than as a precision acoustic platform for localized tissue ablation and biologic modulation, with the most recurrent clinical signal being effective noninvasive treatment of solid or structurally targetable lesions when image guidance, acoustic access, and dose planning are favorable. The most mature and repeatedly represented human evidence concerns uterine fibroids and adenomyosis, where large cohorts reported symptom improvement, quality-of-life gains, fibroid volume reduction, and technical thresholds such as non-perfused volume ratio near or…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"digital::HIFU_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=digital::HIFU_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=digital%3A%3AHIFU_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=digital%3A%3AHIFU_PM\""}}}