


{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"longevity::E_CIGARETTE_BRONCHIOLITIS_OBLITERANS_PM","issue_slug":"longevity","doc_id":"E_CIGARETTE_BRONCHIOLITIS_OBLITERANS_PM","title":"E-Cigarette Use, Bronchiolitis Obliterans, and Constrictive Bronchiolitis","doi":"10.62487/saimsarac97ceff8","doi_url":"https://doi.org/10.62487/saimsarac97ceff8","version":"2026-05-30","source_name":"PubMed","article_url":"https://saimsara.com/sessions/cigarette-bronchiolitis-obliterans-constrictive-bronchioliti-20260530-073819-c97ceff8/","image_url":"https://youtu.be/9QntcrRyibs","topic_tags":"e-cigarette,vaping,bronchiolitis obliterans,constrictive bronchiolitis,diacetyl,flavoring-related lung disease,small airway fibrosis,popcorn lung,occupational lung disease,lung transplantation","keywords":["e-cigarette","vaping","bronchiolitis obliterans","constrictive bronchiolitis","diacetyl","flavoring-related lung disease","small airway fibrosis","popcorn lung","occupational lung disease","lung transplantation"],"metrics":{"included_all":56,"included_original":34,"reference_index":46,"total_participants":1656},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=longevity%3A%3AE_CIGARETTE_BRONCHIOLITIS_OBLITERANS_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=longevity%3A%3AE_CIGARETTE_BRONCHIOLITIS_OBLITERANS_PM","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":13163,"preview":"Results Key finding aligned to the query: The most central and query-defining signal across the included evidence is the convergence of chemical, clinical, and histopathological data supporting a biologically plausible and clinically observed but still low-certainty link between e-cigarette aerosol inhalation and the development of constrictive bronchiolitis. Chemical analyses of flavored e-cigarette products consistently detected diacetyl, a compound causally associated with bronchiolitis obliterans in occupational cohorts, in a majority of tested samples, with concentrations up to 239 μg per e-cigarette, alongside methylglyoxal, an alpha-dicarbonyl more cytotoxic to airway epithelial cells…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"longevity::E_CIGARETTE_BRONCHIOLITIS_OBLITERANS_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=longevity::E_CIGARETTE_BRONCHIOLITIS_OBLITERANS_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=longevity%3A%3AE_CIGARETTE_BRONCHIOLITIS_OBLITERANS_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=longevity%3A%3AE_CIGARETTE_BRONCHIOLITIS_OBLITERANS_PM\""}}}