{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"longevity::GUARANA_PM","issue_slug":"longevity","doc_id":"GUARANA_PM","title":"Guarana and Health","doi":"10.62487/saimsarab08b44a9","doi_url":"https://doi.org/10.62487/saimsarab08b44a9","version":"2026-03-29","source_name":"PubMed","article_url":"https://saimsara.com/sessions/guarana-health-20251203-123923-b08b44a9/","image_url":"","topic_tags":"Paullinia cupana,Cognitive performance,Antioxidant activity,Metabolomic profiling,Anti-adipogenic potential,Neuroprotective effects,Lipid metabolism,Physical performance,Oxidative stress,Cytotoxicity","keywords":["Paullinia cupana","Cognitive performance","Antioxidant activity","Metabolomic profiling","Anti-adipogenic potential","Neuroprotective effects","Lipid metabolism","Physical performance","Oxidative stress","Cytotoxicity"],"metrics":{"included_all":202,"included_original":167,"reference_index":161,"total_participants":251199},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=longevity%3A%3AGUARANA_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=longevity%3A%3AGUARANA_PM","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":17018,"preview":"Results Key finding aligned to the query: Guarana and guarana-containing formulations exerts a multi-systemic pharmacological influence characterized by acute enhancements in cognitive performance—specifically alertness, reaction time, and information processing, —and potent metabolic modulation through the inhibition of adipogenesis and the promotion of weight loss. These effects are driven by a synergistic interaction between high concentrations of methylxanthines and specialized polyphenols, which collectively activate antioxidant pathways and modulate lipid metabolism enzymes. While generally beneficial at moderate doses, excessive consumption is linked to significant cardiovascular and…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"longevity::GUARANA_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=longevity::GUARANA_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=longevity%3A%3AGUARANA_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=longevity%3A%3AGUARANA_PM\""}}}