{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::ALI_AND_RUTHERFORD_SS","issue_slug":"vascular","doc_id":"ALI_AND_RUTHERFORD_SS","title":"Acute Limb Ischemia and Rutherford Classification","doi":"10.62487/saimsara0aca7d8d","doi_url":"https://doi.org/10.62487/saimsara0aca7d8d","version":"2026-03-29","source_name":"Semantic Scholar","article_url":"https://saimsara.com/sessions/acute-limb-ischemia-rutherford-classification-20260213-224153-0aca7d8d/","image_url":"","topic_tags":"Acute limb ischemia,Rutherford classification,Limb salvage,Mechanical thrombectomy,Catheter-directed thrombolysis,Amputation risk,Endovascular revascularization,Prognostic factors,Lower extremity ischemia,Thromboembolic occlusion","keywords":["Acute limb ischemia","Rutherford classification","Limb salvage","Mechanical thrombectomy","Catheter-directed thrombolysis","Amputation risk","Endovascular revascularization","Prognostic factors","Lower extremity ischemia","Thromboembolic occlusion"],"metrics":{"included_all":296,"included_original":275,"reference_index":63,"total_participants":841948},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3AALI_AND_RUTHERFORD_SS","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3AALI_AND_RUTHERFORD_SS","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":14325,"preview":"Results Key finding aligned to the query: The Rutherford classification serves as a robust independent predictor of clinical outcomes, where higher classes (IIb and III) are consistently associated with increased risks of major amputation and mortality. While limb salvage rates remain high for lower Rutherford classes (median 92.5%, range 79.2%–98.2%), presentation with Rutherford III is associated with a dramatic decline in salvage (8%) and a significant increase in mortality (15%). Furthermore, Rutherford Class IIb is a critical threshold that identifies limbs at immediate risk, frequently requiring ultra-early intervention and serving as a primary predictor for post-reperfusion compartmen…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::ALI_AND_RUTHERFORD_SS"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::ALI_AND_RUTHERFORD_SS\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3AALI_AND_RUTHERFORD_SS","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3AALI_AND_RUTHERFORD_SS\""}}}