


{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::ATHEROSCLEROSIS_PREVALENCE_PM","issue_slug":"vascular","doc_id":"ATHEROSCLEROSIS_PREVALENCE_PM","title":"Atherosclerosis Prevalence","doi":"10.62487/saimsara4cd28ee4","doi_url":"https://doi.org/10.62487/saimsara4cd28ee4","version":"2026-04-24","source_name":"PubMed","article_url":"https://saimsara.com/sessions/atherosclerosis-prevalence-20260424-174325-4cd28ee4/","image_url":"","topic_tags":"Subclinical atherosclerosis,Coronary artery calcium,Carotid atherosclerosis,Cardiovascular risk factors,Systemic inflammation,Sex differences,Intracranial atherosclerosis,Abdominal aortic calcification,Vascular imaging,Disease prevalence","keywords":["Subclinical atherosclerosis","Coronary artery calcium","Carotid atherosclerosis","Cardiovascular risk factors","Systemic inflammation","Sex differences","Intracranial atherosclerosis","Abdominal aortic calcification","Vascular imaging","Disease prevalence"],"metrics":{"included_all":2485,"included_original":2307,"reference_index":177,"total_participants":9806460},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3AATHEROSCLEROSIS_PREVALENCE_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3AATHEROSCLEROSIS_PREVALENCE_PM","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":24529,"preview":"Results Key finding aligned to the query: Subclinical atherosclerosis is highly prevalent across the lifespan, with evidence of fatty streaks and lesions appearing as early as ages 15–34. In middle-aged and elderly populations, the prevalence of imaging-detected plaques often exceeds 50%, with male sex and advancing age serving as the most consistent predictors. Notably, systemic inflammatory conditions such as rheumatoid arthritis (RA), psoriasis, and HIV infection, are associated with a significantly higher prevalence of atherosclerosis independent of traditional cardiovascular risk factors. Original research topic synthesis (ordered by evidence hierarchy): Temporal trends in prevalence…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::ATHEROSCLEROSIS_PREVALENCE_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::ATHEROSCLEROSIS_PREVALENCE_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3AATHEROSCLEROSIS_PREVALENCE_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3AATHEROSCLEROSIS_PREVALENCE_PM\""}}}