{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::CEREBRAL_HYPERPERFUSION_PM","issue_slug":"vascular","doc_id":"CEREBRAL_HYPERPERFUSION_PM","title":"Cerebral Hyperperfusion Syndrome","doi":"10.62487/saimsara6ed87781","doi_url":"https://doi.org/10.62487/saimsara6ed87781","version":"2026-05-26","source_name":"PubMed","article_url":"https://saimsara.com/sessions/cerebral-hyperperfusion-syndrome-20260526-172734-6ed87781/","image_url":"","topic_tags":"Cerebral hyperperfusion syndrome,Carotid endarterectomy,Carotid artery stenting,Moyamoya disease,Cerebral revascularization,Cerebrovascular reserve,Circle of Willis,Transcranial Doppler,Arterial spin labeling,Hypertension","keywords":["Cerebral hyperperfusion syndrome","Carotid endarterectomy","Carotid artery stenting","Moyamoya disease","Cerebral revascularization","Cerebrovascular reserve","Circle of Willis","Transcranial Doppler","Arterial spin labeling","Hypertension"],"metrics":{"included_all":586,"included_original":475,"reference_index":192,"total_participants":477299},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3ACEREBRAL_HYPERPERFUSION_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ACEREBRAL_HYPERPERFUSION_PM","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":28235,"preview":"Results Key finding aligned to the query: Across the included original studies, the most consistent paper-level finding is that CHS represents a reperfusion-autoregulation mismatch: chronically impaired cerebrovascular reserve (CVR), exhausted collateral physiology, and perioperative blood pressure instability make restored flow clinically hazardous after carotid, bypass, and endovascular procedures. This recurring signal appears across CEA, CAS, extracranial-intracranial bypass, and MMD revascularization studies, where low reserve or abnormal perfusion testing, abrupt cerebral blood flow (CBF) increases, and hypertension repeatedly identify higher-risk patients rather than any single biomar…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::CEREBRAL_HYPERPERFUSION_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::CEREBRAL_HYPERPERFUSION_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ACEREBRAL_HYPERPERFUSION_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ACEREBRAL_HYPERPERFUSION_PM\""}}}