{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::CLTI_PROGNOSIS_SS","issue_slug":"vascular","doc_id":"CLTI_PROGNOSIS_SS","title":"CLTI Prognosis and Chronic Limb-Threatening Ischemia Outcomes","doi":"10.62487/saimsara9e1c0fc3","doi_url":"https://doi.org/10.62487/saimsara9e1c0fc3","version":"2026-05-01","source_name":"Semantic Scholar","article_url":"https://saimsara.com/sessions/clti-prognosis-20260501-181746-9e1c0fc3/","image_url":"","topic_tags":"Amputation-free survival,Chronic limb-threatening ischemia,Endovascular treatment,WIfI clinical stage,Hemodialysis,Heart failure,Nutritional risk index,Major amputation,All-cause mortality,Revascularization","keywords":["Amputation-free survival","Chronic limb-threatening ischemia","Endovascular treatment","WIfI clinical stage","Hemodialysis","Heart failure","Nutritional risk index","Major amputation","All-cause mortality","Revascularization"],"metrics":{"included_all":81,"included_original":74,"reference_index":69,"total_participants":392683},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3ACLTI_PROGNOSIS_SS","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ACLTI_PROGNOSIS_SS","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":15687,"preview":"Results Key finding aligned to the query: Prognosis in CLTI is most robustly predicted by a combination of wound severity, nutritional status, and systemic frailty. Wound, Ischemia, and foot Infection (WIfI) stage repeatedly stratified mortality, limb outcomes, and amputation-free survival (AFS), while the Geriatric Nutritional Risk Index (GNRI), GNRI-based nutritional-risk assessment, and composite prognostic scores incorporating GNRI, age, anemia, heart failure, sex, or hemodialysis showed strong long-term AFS discrimination. Across studies, 1-year AFS ranges from approximately 45.7% in non-revascularized patients to 90% in the GNRI no-risk group, while GNRI-containing prognostic scores re…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::CLTI_PROGNOSIS_SS"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::CLTI_PROGNOSIS_SS\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ACLTI_PROGNOSIS_SS","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ACLTI_PROGNOSIS_SS\""}}}