{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::CO2_ANGIOGRAPHY_PM","issue_slug":"vascular","doc_id":"CO2_ANGIOGRAPHY_PM","title":"Carbon Dioxide CO2 Angiography for Kidney-Sparing Vascular Imaging and Interventions","doi":"10.62487/saimsara565e9b06","doi_url":"https://doi.org/10.62487/saimsara565e9b06","version":"2026-05-22","source_name":"PubMed","article_url":"https://saimsara.com/sessions/co2-angiography-20260522-190427-565e9b06/","image_url":"","topic_tags":"Carbon dioxide angiography,Digital subtraction angiography,Peripheral arterial disease,Chronic kidney disease,Iodinated contrast,Contrast-induced nephropathy,Endovascular therapy,Renal angioplasty,Image quality,Vascular complications","keywords":["Carbon dioxide angiography","Digital subtraction angiography","Peripheral arterial disease","Chronic kidney disease","Iodinated contrast","Contrast-induced nephropathy","Endovascular therapy","Renal angioplasty","Image quality","Vascular complications"],"metrics":{"included_all":117,"included_original":105,"reference_index":93,"total_participants":4202},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3ACO2_ANGIOGRAPHY_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ACO2_ANGIOGRAPHY_PM","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":23305,"preview":"Results Key finding aligned to the query: The central finding across the included original studies is that CO2 angiography is best supported as a kidney-sparing and allergy-avoiding contrast strategy for selected endovascular and diagnostic procedures, particularly in peripheral, renal, transplant, dialysis-access, and aortic interventions, rather than as a universal replacement for ICM. Representative evidence includes large clinical experience showing acceptable morbidity and no significant renal-function impact across 1007 CO2 digital subtraction angiography (DSA) procedures, randomized or comparative data showing reduced renal impairment risk when CO2 limits iodine exposure, and EVAR dat…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::CO2_ANGIOGRAPHY_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::CO2_ANGIOGRAPHY_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ACO2_ANGIOGRAPHY_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ACO2_ANGIOGRAPHY_PM\""}}}