{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::DAPT_PM","issue_slug":"vascular","doc_id":"DAPT_PM","title":"Dual Antiplatelet Therapy Across Clinical Indications — Ischemic Outcomes, Bleeding Risks, and Treatment Strategies","doi":"10.62487/saimsara0eb77a90","doi_url":"https://doi.org/10.62487/saimsara0eb77a90","version":"2026-11-10","source_name":"PubMed","article_url":"https://saimsara.com/sessions/dual-antiplatelet-therapy-20260601-093033-0eb77a90/","image_url":"","topic_tags":"Dual antiplatelet therapy,Aspirin,P2Y12 inhibitors,Ischemic stroke,Acute coronary syndrome,Endovascular interventions,Bleeding risk,Thromboembolic complications,Antiplatelet therapy duration,Single antiplatelet therapy","keywords":["Dual antiplatelet therapy","Aspirin","P2Y12 inhibitors","Ischemic stroke","Acute coronary syndrome","Endovascular interventions","Bleeding risk","Thromboembolic complications","Antiplatelet therapy duration","Single antiplatelet therapy"],"metrics":{"included_all":8641,"included_original":5437,"reference_index":1090,"total_participants":42127523},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3ADAPT_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ADAPT_PM","price":{"amount":"12.00","currency":"USD","units":12,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":129792,"preview":"4) Results Key Finding Aligned To The Query: The dominant finding across the mapped evidence is that DAPT offers an indication- and time-dependent balance between ischemic protection and bleeding, rather than a consistently favorable effect across all populations. In selected coronary stent recipients, extending treatment beyond one year reduced stent thrombosis compared with stopping the thienopyridine while continuing aspirin (0.4% versus 1.4%), but increased moderate or severe bleeding (2.5% versus 1.6%). Conversely, among selected patients at high bleeding risk, abbreviated treatment produced similar net adverse clinical event rates and less major or clinically relevant nonmajor bleeding…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::DAPT_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"12.00","currency":"USD","units":12,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::DAPT_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ADAPT_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ADAPT_PM\""}}}