{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::FRACTIONAL_FLOW_RESERVE_PM","issue_slug":"vascular","doc_id":"FRACTIONAL_FLOW_RESERVE_PM","title":"Fractional Flow Reserve","doi":"10.62487/saimsara5168025d","doi_url":"https://doi.org/10.62487/saimsara5168025d","version":"2026-05-25","source_name":"PubMed","article_url":"https://saimsara.com/sessions/fractional-flow-reserve-20260525-180030-5168025d/","image_url":"","topic_tags":"Fractional flow reserve,Coronary artery disease,Coronary angiography,Intermediate coronary lesions,Percutaneous coronary intervention,Stable angina,Adenosine hyperemia,Instantaneous wave-free ratio,Coronary flow reserve,Virtual FFR","keywords":["Fractional flow reserve","Coronary artery disease","Coronary angiography","Intermediate coronary lesions","Percutaneous coronary intervention","Stable angina","Adenosine hyperemia","Instantaneous wave-free ratio","Coronary flow reserve","Virtual FFR"],"metrics":{"included_all":4876,"included_original":3488,"reference_index":615,"total_participants":42464789},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3AFRACTIONAL_FLOW_RESERVE_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3AFRACTIONAL_FLOW_RESERVE_PM","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":57535,"preview":"Results Key finding aligned to the query: The most central and recurrent finding is that FFR functions as a clinically actionable physiologic reference standard that frequently reclassifies angiography-based coronary decision-making and supports safer, more selective revascularization. Across landmark randomized and registry evidence, FFR-guided percutaneous coronary intervention (PCI) reduced stent use and adverse events compared with angiography-guided PCI in multivessel disease, while FFR-guided deferral was generally safe when FFR was above ischemic thresholds. This signal recurred in real-world cohorts where FFR changed management in roughly one third to nearly one half of patients or l…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::FRACTIONAL_FLOW_RESERVE_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::FRACTIONAL_FLOW_RESERVE_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3AFRACTIONAL_FLOW_RESERVE_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3AFRACTIONAL_FLOW_RESERVE_PM\""}}}