{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::LARVAL_THERAPY_PM","issue_slug":"vascular","doc_id":"LARVAL_THERAPY_PM","title":"Larval Therapy for Chronic Wounds","doi":"10.62487/saimsara9407ba6d","doi_url":"https://doi.org/10.62487/saimsara9407ba6d","version":"2026-04-29","source_name":"PubMed","article_url":"https://saimsara.com/sessions/larval-therapy-20260429-160201-9407ba6d/","image_url":"","topic_tags":"Larval therapy,Maggot debridement therapy,Wound healing,Diabetic foot ulcers,Venous leg ulcers,Lucilia sericata,Biodebridement,Chronic wounds,Cost-effectiveness,Necrotic tissue","keywords":["Larval therapy","Maggot debridement therapy","Wound healing","Diabetic foot ulcers","Venous leg ulcers","Lucilia sericata","Biodebridement","Chronic wounds","Cost-effectiveness","Necrotic tissue"],"metrics":{"included_all":128,"included_original":93,"reference_index":97,"total_participants":11977},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3ALARVAL_THERAPY_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ALARVAL_THERAPY_PM","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":17572,"preview":"Results Study-Level Evidence Map: Effect-of Predictor → Outcome larval therapy → Outcome Favorable ΣN=10849 (91%) Unfavorable ΣN=215 (2%) Neutral ΣN=913 (8%) Key finding aligned to the query: Larval therapy significantly accelerates debridement of necrotic and sloughy tissue compared with hydrogel or conventional dressings, with evidence from VenUS II reported in both the full HTA report and BMJ trial publication for venous/mixed leg ulcers, and from randomized diabetic-ulcer data comparing free-range versus bagged larvae. This efficacy is mediated by a synergistic systems-level mechanism involving the secretion of serine proteases (trypsin and chymotrypsin) that liquefy eschar, and the rele…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::LARVAL_THERAPY_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::LARVAL_THERAPY_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ALARVAL_THERAPY_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ALARVAL_THERAPY_PM\""}}}