{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::PAD_MEDICATION_PM","issue_slug":"vascular","doc_id":"PAD_MEDICATION_PM","title":"Peripheral Artery Disease and Medical Therapy","doi":"10.62487/saimsara3b5bca76","doi_url":"https://doi.org/10.62487/saimsara3b5bca76","version":"2026-04-03","source_name":"PubMed","article_url":"https://saimsara.com/sessions/peripheral-artery-disease-medication-20260403-212905-3b5bca76/","image_url":"","topic_tags":"Peripheral artery disease,Antiplatelet therapy,Statin therapy,Antithrombotic therapy,Intermittent claudication,Optimal medical therapy,Major adverse limb events,Medication adherence,Type 2 diabetes,Cardiovascular risk reduction","keywords":["Peripheral artery disease","Antiplatelet therapy","Statin therapy","Antithrombotic therapy","Intermittent claudication","Optimal medical therapy","Major adverse limb events","Medication adherence","Type 2 diabetes","Cardiovascular risk reduction"],"metrics":{"included_all":195,"included_original":180,"reference_index":81,"total_participants":2662177},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3APAD_MEDICATION_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3APAD_MEDICATION_PM","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":18646,"preview":"Results Key finding aligned to the query: The most consistent finding across the literature is the persistent underutilization of guideline-directed medical therapy (GDMT)—specifically statins, antiplatelets, and angiotensin-converting enzyme (ACE) inhibitors—in PAD populations compared to those with coronary artery disease (CAD), despite evidence that GDMT is associated with a 67% reduction in all-cause mortality (aHR 0.329 ) and significant reductions in MACE (HR 0.46–0.80 ). Real-world data indicate that statin use can be as low as 19.7% in some vascular clinics, and even after revascularization, more than two-thirds of patients not previously on statins remain untreated at discharge. Fur…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::PAD_MEDICATION_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::PAD_MEDICATION_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3APAD_MEDICATION_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3APAD_MEDICATION_PM\""}}}