{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::PATHOPHYSIOLOGY_OF_DVT_SS","issue_slug":"vascular","doc_id":"PATHOPHYSIOLOGY_OF_DVT_SS","title":"Pathophysiology of Deep Venous Thrombosis","doi":"10.62487/saimsara66525623","doi_url":"https://doi.org/10.62487/saimsara66525623","version":"2026-03-17","source_name":"Semantic Scholar","article_url":"https://saimsara.com/sessions/deep-venous-thrombosis-pathophysiology-20260317-110402-66525623/","image_url":"","topic_tags":"Deep Venous Thrombosis,Pathophysiology,Neutrophil Extracellular Traps,Platelet Activation,Endothelial Dysfunction,Inflammation,Coagulation,Animal Models,Cancer-Associated Thrombosis,Postthrombotic Syndrome","keywords":["Deep Venous Thrombosis","Pathophysiology","Neutrophil Extracellular Traps","Platelet Activation","Endothelial Dysfunction","Inflammation","Coagulation","Animal Models","Cancer-Associated Thrombosis","Postthrombotic Syndrome"],"metrics":{"included_all":257,"included_original":155,"reference_index":96,"total_participants":1552714},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3APATHOPHYSIOLOGY_OF_DVT_SS","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3APATHOPHYSIOLOGY_OF_DVT_SS","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":11579,"preview":"Results Key finding aligned to the query: The pathophysiology of deep venous thrombosis is predominantly driven by a complex interplay of inflammation, immune cell activation (particularly neutrophils and their extracellular traps), and endothelial dysfunction, frequently exacerbated by underlying conditions such as cancer, inflammatory disorders, or genetic predispositions. Platelet activation and subsequent recruitment of leukocytes, alongside the release of procoagulant neutrophil extracellular traps (NETs), are consistently identified as central mechanisms in thrombus initiation and stability. Furthermore, chronic inflammation and endothelial injury contribute significantly to DVT progre…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::PATHOPHYSIOLOGY_OF_DVT_SS"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::PATHOPHYSIOLOGY_OF_DVT_SS\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3APATHOPHYSIOLOGY_OF_DVT_SS","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3APATHOPHYSIOLOGY_OF_DVT_SS\""}}}