{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::STATIN_SS","issue_slug":"vascular","doc_id":"STATIN_SS","title":"Statin","doi":"10.62487/f5760313","doi_url":"https://doi.org/10.62487/f5760313","version":"2026-03-10","source_name":"PubMed","article_url":"https://saimsara.com/sessions/statin-20260216-203659-f5760313/","image_url":"https://saimsara.com/sessions/statin-20260216-203659-f5760313/osma.jpg","topic_tags":"Statins,Type 2 diabetes mellitus,Atrial fibrillation,Heart failure,Dementia,Chronic kidney disease,Adverse drug reactions,Lipoprotein,Acute myocardial infarction,Sepsis-associated acute kidney injury","keywords":["Statins","Type 2 diabetes mellitus","Atrial fibrillation","Heart failure","Dementia","Chronic kidney disease","Adverse drug reactions","Lipoprotein","Acute myocardial infarction","Sepsis-associated acute kidney injury"],"metrics":{"included_all":5577,"included_original":4734,"reference_index":369,"total_participants":141699669},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3ASTATIN_SS","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ASTATIN_SS","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":17339,"preview":"Results Key finding aligned to the query: Statin therapy demonstrates significant benefits in reducing major adverse cardiovascular events (MACE) and mortality across various high-risk populations. For instance, early statin initiation in statin-naïve patients with acute myocardial infarction (AMI) reduces long-term MACE by 19% (Hazard Ratio (HR) 0.81, 95% CI 0.67-0.97), and statin use is associated with a lower risk of heart failure (HR 0.81, 95% CI 0.78-0.85) in patients with atrial fibrillation. Concurrently, statins are associated with an increased risk of incident Type 2 Diabetes (T2D), notably higher in hypertensive patients (HR 4.62, 95% CI 3.75-5.69), and can significantly increase p…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::STATIN_SS"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::STATIN_SS\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ASTATIN_SS","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ASTATIN_SS\""}}}