{"ok":true,"api":{"name":"SAIMSARA Evidence Object Discovery API","version":"v1"},"mode":"doc_key","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"object":{"object_type":"saimsara_evidence_object_metadata","doc_key":"vascular::TCAR_VS_CAS_PM","issue_slug":"vascular","doc_id":"TCAR_VS_CAS_PM","title":"Transcarotid Artery Revascularization vs Carotid Artery Stenting","doi":"10.62487/saimsara1247267","doi_url":"https://doi.org/10.62487/saimsara1247267","version":"2026-04-02","source_name":"PubMed","article_url":"https://saimsara.com/sessions/tcar-cas-20251124-214631-d1247267/","image_url":"","topic_tags":"Transcarotid artery revascularization,Carotid artery stenting,Carotid endarterectomy,Carotid artery stenosis,Stroke risk,Vascular Quality Initiative,Transfemoral carotid stenting,Cerebral hyperperfusion syndrome,Perioperative outcomes,Flow reversal, CAS, TCAR, Stroke","keywords":["Transcarotid artery revascularization","Carotid artery stenting","Carotid endarterectomy","Carotid artery stenosis","Stroke risk","Vascular Quality Initiative","Transfemoral carotid stenting","Cerebral hyperperfusion syndrome","Perioperative outcomes","Flow reversal","CAS","TCAR","Stroke"],"metrics":{"included_all":41,"included_original":37,"reference_index":24,"total_participants":1685306},"discover_url":"https://saimsara.com/api/v1/discover.php?doc_key=vascular%3A%3ATCAR_VS_CAS_PM","paid_evidence_url":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ATCAR_VS_CAS_PM","price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"payment_methods":["api_key","stripe_checkout","object_grant","x402"],"text_length":9370,"preview":"Results Study-Level Evidence Map: Favours tcar ΣN=607067 (36%) Favours cas ΣN=40835 (2%) Neutral ΣN=1037404 (62%) Key finding aligned to the query: TCAR consistently demonstrates superior safety profiles compared to TF-CAS, evidenced by a significant reduction in perioperative stroke and death across multiple large-scale cohorts. In longitudinal analysis, TCAR was associated with a lower 3-year stroke risk compared to TF-CAS in both asymptomatic (5.1% vs 9.2%) and symptomatic (16.6% vs 20.9%) patients. Furthermore, TCAR reduces the risk of cerebral hyperperfusion syndrome (CHS) and provides better neuroprotection than distal embolic protection (DEP) filters used in traditional stenting. Orig…","trust_label":"machine_generated_human_reviewed","editorial_verification":{"status":"human_reviewed","trust_label":"machine_generated_human_reviewed","method":"World ID proof-of-human editorial account","scope":["clinical_integrity","reference_quality","scientific_coherence"],"verification_note":"This Evidence Object is machine-generated and human-reviewed. World ID is used to verify that editorial oversight was submitted by a unique human account.","does_not_mean":"World ID verifies proof-of-human editorial oversight; it does not independently certify the scientific truth of every claim."},"checkout":{"method":"POST","url":"https://saimsara.com/create_checkout_session.php","content_type":"application/x-www-form-urlencoded","params":{"plan":"evidence_object","doc_key":"vascular::TCAR_VS_CAS_PM"},"optional_params":{"customer_email":"user@example.com"},"price":{"amount":"5.00","currency":"USD","units":5,"unit_amount":"1.00"},"curl_example":"curl -X POST https://saimsara.com/create_checkout_session.php -d \"plan=evidence_object\" -d \"doc_key=vascular::TCAR_VS_CAS_PM\" -d \"customer_email=user@example.com\""},"access_after_payment":{"header":"X-SAIMSARA-Payment-Proof","endpoint":"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ATCAR_VS_CAS_PM","curl_example":"curl -H \"X-SAIMSARA-Payment-Proof: YOUR_PAYMENT_PROOF_TOKEN\" \"https://saimsara.com/api/v1/evidence.php?doc_key=vascular%3A%3ATCAR_VS_CAS_PM\""}}}