SAIMSARA Journal

Machine-Readable Science • ISSN 3054-3991

SMS-Based Patient Outreach for Appointment Attendance, Medication Adherence, and Screening Uptake: Scoping Review with ☸️SAIMSARA

Digital Health & Biotech icon

Digital Health & Biotech

Issue 3, Volume 1, 2026

DOI: 10.62487/saimsara3165b1f4

Editorial note
• Last update: 2026-06-10 10:18:08
What is this paper about
SMS outreach can improve appointment attendance, medication adherence, screening uptake, and chronic disease engagement—but its success depends strongly on message design, personalization, and patient context. The full read reveals which strategies work best, where SMS falls short, and how it should be integrated into broader patient-outreach systems.
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Abstract: To comprehensively map the original research literature on SMS-based patient outreach, synthesizing its applications, effectiveness, and implementation characteristics across clinical domains, populations, and settings. The review uses 43 references and builds its evidence map from 144 original studies with 5742095 total participants/sample observations (topic-deduplicated ΣN). Overall, this scoping review suggests that SMS-based patient outreach is a versatile and broadly effective tool for strengthening healthcare engagement, with the most consistent signals seen in appointment adherence, medication refill behavior, and screening uptake. Interactive, tailored, and multimodal designs were associated with substantial gains in several settings, including a 14.07 percentage point increase in refill rates with tailored messaging and 72.9% colorectal cancer screening adherence when SMS was combined with email. However, effectiveness was moderated by age, digital literacy, and socioeconomic factors, indicating that SMS alone is unlikely to close equity gaps. Practically, these findings support embedding SMS within layered outreach workflows rather than as a standalone channel. Future research should prioritize equity-focused, long-term trials that test personalized and multimodal SMS strategies against standard outreach to clarify durability and reach in underserved populations.
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Keywords: SMS-based patient outreach; appointment reminders; medication adherence; patient engagement; mHealth interventions; digital health communication; treatment initiation; patient-reported outcomes; healthcare access; chronic disease management

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Reference Index (43)

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