Flow Diverters for Aneurysm Treatment: Scoping Review with ☸️SAIMSARA.

Name: SAIMSARA Evidence Object vascular::FLOW_DIVERTERS_PM
Creator: SAIMSARA
License: https://saimsara.com/license/

SAIMSARA

doi:10.62487/saimsara0494831d

SAIMSARA Journal

Machine-Readable Science • ISSN 3054-3991

Flow Diverters for Aneurysm Treatment: Scoping Review with ☸️SAIMSARA.

Cardiac & Vascular Health

Issue 1, Volume 1, 2026

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DOI: 10.62487/saimsara0494831d

Editorial note

• Last update: 2026-05-30 12:33:00

What is this paper about

Flow diverters have reshaped aneurysm treatment, but their success depends heavily on anatomy, device behavior, and procedural strategy. The full read maps 252 references and 1439 original studies to separate strong indications from high-risk zones, giving a practical evidence overview for clinicians, researchers, and endovascular teams.

Human-verified editorial review Verified by World ID proof-of-human. This editorial layer was submitted from a SAIMSARA account verified as a unique human.

Abstract: To synthesize the structured extraction evidence on “flow diverter” studies, emphasizing clinical effectiveness, safety, mechanistic rationale, procedural determinants, device evolution, imaging follow-up, antiplatelet strategy, and research directions relevant to FD use. The review uses 252 references and builds its evidence map from 1439 original studies with 161646 total participants/sample observations (topic-deduplicated ΣN). Across this evidence map, flow diversion emerges as a mature but selection-sensitive reconstructive therapy whose benefit is conditional on matching aneurysm anatomy, device mechanics, and periprocedural management. The most consistent signal supports durable occlusion in large, giant, wide-neck, and internal carotid aneurysms, with randomized data showing 75.34% versus 24.53% complete occlusion favoring Tubridge over stent-assisted coiling and Surpass reaching 90.2% occlusion at 5 years, while middle cerebral bifurcation, fetal-type posterior communicating, branch-incorporated, and acutely ruptured lesions remain higher-risk indications. Deployment quality, apposition, sizing, and antiplatelet strategy repeatedly emerged as modifiable determinants of outcome rather than fixed device properties. The dominant uncertainty is comparative: head-to-head randomized trials in anatomically defined subgroups, paired with harmonized occlusion and complication endpoints, are the priority next step to convert this largely retrospective signal into actionable guidance.

Keywords: Flow diverter; Intracranial aneurysm; Endovascular treatment; Aneurysm occlusion; Pipeline embolization device; Tubridge flow diverter; Stent deployment; Parent artery; In-stent stenosis; Posterior circulation

Review Stats

Final search date and database lock: 2026-05-21 20:33:16 CEST
Plan: Pro (expanded craft tokens; source: PubMed)
Source: PubMed
Total Abstracts/Papers: 2172
Downloaded Abstracts/Papers: 2172
Included original and non-original Abstracts/Papers (all): 1644
Included original Abstracts/Papers (Vote counting by direction of effect): 1439
Reference Index (links used in paper): 252
Total participants/sample observations (topic deduplicated ΣN): 161646

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Reference Index (252)

[1] Flow diverter treatment of intracranial vertebral artery dissecting pseudoaneurysms. — https://doi.org/10.1136/neurintsurg-2017-013020
[2] Flow-diverter devices in the treatment of intracranial aneurysms: A meta-analysis and systematic review. — https://doi.org/10.1177/1971400915621321
[3] Tubridge flow diverter for the treatment of small and medium aneurysms. — https://doi.org/10.3389/fneur.2023.1054631
[4] The Silk flow-diverter stent for endovascular treatment of intracranial aneurysms. — https://doi.org/10.1586/17434440.2015.1093413
[5] Robotically assisted deployment of flow diverter stents for the treatment of cerebral and cervical aneurysms. — https://doi.org/10.1136/jnis-2022-019968
[6] Predicting flow diverter sizing using the AneuGuide software: a validation study. — https://doi.org/10.1136/neurintsurg-2021-018353
[7] Parent Artery Straightening after Flow-Diverter Stenting Improves the Odds of Aneurysm Occlusion. — https://doi.org/10.3174/ajnr.a7350
[8] Endovascular techniques for achievement of better flow diverter wall apposition. — https://doi.org/10.1177/1591019918815294

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