Infection Prevention Maintenance Strategies for Central Venous Catheters: Scoping Review with ☸️SAIMSARA

Name: SAIMSARA Evidence Object infections::INFECTION_PREVENTION_CVC_SS
Creator: SAIMSARA
License: https://saimsara.com/license/

SAIMSARA

doi:10.62487/saimsaradd9bd2f2

SAIMSARA Journal

Machine-Readable Science • ISSN 3054-3991

Infection Prevention Maintenance Strategies for Central Venous Catheters: Scoping Review with ☸️SAIMSARA

Infectious Diseases

Issue 7, Volume 1, 2026

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DOI: 10.62487/saimsaradd9bd2f2

Editorial note

• Last update: 2026-06-03 21:38:35

What is this paper about

Central venous catheter infection prevention is not a single-product story: this review shows that sustained Central Line-Associated Bloodstream Infection/Catheter-Related Bloodstream Infection (CLABSI/CRBSI) reduction depends on maintenance bundles, chlorhexidine-based care, closed-access systems, daily line-necessity review, staff competency, and audit feedback working together. Built from 326 original studies and 608,263 participant/sample observations, the full read maps where infection rates fall by 42% to over 90%, where risk persists despite bundles, and which maintenance strategies are most clinically actionable across adult, pediatric, neonatal, oncology, and hemodialysis populations.

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Abstract: To systematically map and synthesize the published evidence on infection prevention maintenance strategies for central venous catheters, identifying effective interventions, persistent risk factors, knowledge gaps, and implementation outcomes across adult, pediatric, and neonatal populations. The review uses 124 references and builds its evidence map from 326 original studies with 608263 total participants/sample observations (topic-deduplicated ΣN). This scoping review indicates that comprehensive, multicomponent maintenance bundles—combining chlorhexidine-based antisepsis, standardized dressings, closed-access systems, daily line-necessity assessment, and staff education with audit and feedback—were the most consistently replicated strategy associated with reduced CLABSI/CRBSI across adult, pediatric, and hemodialysis populations, with reported reductions ranging from 42% to over 90%. Recurrent signals support a role for limiting modifiable risk, particularly prolonged catheter dwell time, with rates rising from 4.80 to 8.64 per 1000 catheter-days beyond 20 days. The evidence highlights that sustaining gains depends on ongoing monitoring and reliable bundle adherence rather than any single device or product, suggesting that prompt removal of unnecessary lines and continuous competency-based training are practical priorities. Because most signals arise from heterogeneous observational designs without formal appraisal, future multicenter trials should clarify which bundle components and dwell-time thresholds drive the greatest benefit, especially in lower-resource settings.
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Keywords: Central venous catheter; Infection prevention; Maintenance bundle; Catheter-related bloodstream infection; CLABSI surveillance; Chlorhexidine antisepsis; Needle-free connector; Hemodialysis catheter care; Pediatric CVC maintenance; Bundle compliance audit

Review Stats

Final search date and database lock: 2026-06-01 21:53:20 CEST
Plan: Pro (expanded craft tokens; source: Semantic Scholar)
Source: Semantic Scholar
Total Abstracts/Papers: 2864
Downloaded Abstracts/Papers: 1000
Included original and non-original Abstracts/Papers (all): 535
Included original Abstracts/Papers (Vote counting by direction of effect): 326
Reference Index (links used in paper): 124
Total participants/sample observations (topic deduplicated ΣN): 608263

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Reference Index (124)

[1] Nursing Care and Pharmacists Management of Central Venous Catheters: Evidence-Based Practices for Safety and Infection Prevention — https://doi.org/10.64483/202522302
[2] Development of best evidence-based practice protocols for central venous catheter placement and maintenance to reduce CLABSI — https://doi.org/10.1097/md.0000000000038652
[3] Central venous catheter bundle adherence: Kamishibai card (K-card) rounding for central-line–associated bloodstream infection (CLABSI) prevention — https://doi.org/10.1017/ice.2020.235
[4] Prevention of central venous line associated bloodstream infections- A literature review — https://doi.org/10.38106/lmrj.2024.6.2-08
[5] Risk factors for central line-associated bloodstream infection in the pediatric intensive care setting despite standard prevention measures — https://doi.org/10.1017/ice.2024.131
[6] ANALYZING CENTRAL-LINE ASSOCIATED BLOODSTREAM INFECTION PREVENTION BUNDLES IN 22 COUNTRIES: THE RESULTS OF ID-IRI SURVEY. — https://doi.org/10.1016/j.ajic.2022.02.031
[7] Effects of a Quality Improvement Program to Reduce Central Venous Catheter-Related Infections in Hemodialysis Patients. — https://doi.org/10.1016/j.amjms.2020.10.018
[8] Central line-associated blood stream infections in newborns: From vulnerability to prevention. — https://doi.org/10.1016/j.siny.2025.101665

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