Mesenteric Venous Thrombosis Treatment Outcomes and Prognosis: Scoping Review with ☸️SAIMSARA

Name: SAIMSARA Evidence Object vascular::MVT_PM
Creator: SAIMSARA
License: https://saimsara.com/license/

SAIMSARA

doi:10.62487/saimsarae883c7a8

SAIMSARA Journal

Machine-Readable Science • ISSN 3054-3991

Mesenteric Venous Thrombosis Treatment Outcomes and Prognosis: Scoping Review with ☸️SAIMSARA

Cardiac & Vascular Health

Issue 1, Volume 1, 2026

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DOI: 10.62487/saimsarae883c7a8

Editorial note

• Last update: 2026-11-13 13:17:39

What is this paper about

Mesenteric venous thrombosis can be life-threatening, yet earlier diagnosis and evolving treatment strategies are transforming patient outcomes—with one study reporting mortality falling from 39% to 11%. Drawing on 436 scientific references, this review reveals what the evidence says about anticoagulation, endovascular interventions, risk factors, and long-term prognosis—unlock the full review to explore the findings.

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Abstract: To synthesize current evidence regarding mesenteric venous thrombosis. The review uses 436 references and builds its evidence map from 1058 original studies with 159421 total participants/sample observations (topic-deduplicated ΣN). This scoping review suggests that mesenteric venous thrombosis is best approached as a high-risk yet increasingly treatable splanchnic thrombosis in which early cross-sectional imaging and prompt anticoagulation form the management core, with escalation reserved for threatened bowel. Anticoagulation, including both vitamin K antagonists and direct oral agents, was associated with favorable recanalization and low recurrence, and a medical-first policy was associated with reduced mortality from 39% to 11%. Outcomes appear more favorable than arterial mesenteric ischemia, though early mortality and progression to portal hypertensive sequelae remain clinically important. Because the evidence is dominated by case series and uncontrolled cohorts without randomized comparisons, these signals should be interpreted as descriptive patterns rather than confirmed effects. Future prospective comparative trials using standardized recanalization, bowel-preservation, and bleeding endpoints are needed to clarify optimal anticoagulant choice, duration, and the role of endovascular escalation.

Keywords: Mesenteric venous thrombosis; Superior mesenteric vein; Portomesenteric thrombosis; Anticoagulation therapy; Mesenteric ischemia; Computed tomography; Thrombophilia; Appendicitis; Splenectomy; COVID-19

Review Stats

Final search date and database lock: 2026-06-14 10:49:58 CEST
Plan: Pro (expanded craft tokens; source: PubMed)
Source: PubMed
Total Abstracts/Papers: 1714
Downloaded Abstracts/Papers: 1714
Included original and non-original Abstracts/Papers (all): 1306
Included original Abstracts/Papers (Vote counting by direction of effect): 1058
Reference Index (links used in paper): 436
Total participants/sample observations (topic deduplicated ΣN): 159421

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Reference Index (435)

[1] Management of Acute Mesenteric Venous Thrombosis: A Systematic Review of Contemporary Studies. — https://doi.org/10.1177/1457496920969084
[2] Mesenteric venous thrombosis. — https://doi.org/10.1016/j.jceh.2014.03.052
[3] Mesenteric venous thrombosis. — https://doi.org/10.1016/j.mayocp.2013.01.012
[4] Mesenteric venous thrombosis. — https://doi.org/10.1097/00007611-199906000-00002
[5] Acute mesenteric ischemia. — https://doi.org/10.1016/j.suc.2013.10.012
[6] Porto-spleno-mesenteric venous thrombosis after elective splenectomy: a retrospective cohort study. — https://doi.org/10.3389/fimmu.2023.1216283
[7] Mesenteric venous thrombosis: still a lethal disease in the 1990s. — https://doi.org/10.1016/s0741-5214(94)70155-5
[8] [Acute mesenteric ischemia]. — https://doi.org/10.1007/s00063-015-0075-2

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