Popliteal Artery Aneurysm Treatment: Scoping Review with ☸️SAIMSARA.

Name: SAIMSARA Evidence Object vascular::POP_ARTERY_ANEURYSM_TREATMENT_PM
Creator: SAIMSARA
License: https://saimsara.com/license/

SAIMSARA

doi:10.62487/saimsarad4c59ee9

SAIMSARA Journal

Machine-Readable Science • ISSN 3054-3991

Popliteal Artery Aneurysm Treatment: Scoping Review with ☸️SAIMSARA.

Cardiac & Vascular Health

Issue 1, Volume 1, 2026

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DOI: 10.62487/saimsarad4c59ee9

Editorial note

• Last update: 2026-05-10 05:50:23

What is this paper about

Popliteal artery aneurysm treatment is more than open vs endovascular repair: outcome depends on conduit, approach, runoff, thrombus burden, acuity, and sex-specific risk. The full SAIMSARA evidence map gives humans and AI agents a structured, reference-linked view of 188 original studies and the key treatment signals.

Human-verified editorial review Verified by World ID proof-of-human. This editorial layer was submitted from a SAIMSARA account verified as a unique human.

Abstract: The aim of this review is to synthesize current evidence regarding the treatment strategies for popliteal artery aneurysms, comparing the clinical outcomes of open surgical and endovascular interventions, and identifying key prognostic factors across diverse patient populations. The review utilises 188 original studies with 29285 total participants (topic deduplicated ΣN). The mapped evidence indicates that open surgical repair, particularly with autologous saphenous vein and a posterior approach, remains the dominant durable option for popliteal artery aneurysm, with 5-year primary patency reaching 81% versus 64.1% for endovascular repair and 12-month patency of 83.2% versus 44.7% in registry data. Endovascular repair was repeatedly associated with shorter hospitalization and faster recovery but with higher reintervention, falling primary patency from 69.1% at 6 months to 42.6% at 24 months in one cohort, and device-specific concerns at the popliteal hinge point. Recurrent signals across topics support early elective intervention for aneurysms exceeding 20 mm, adjunctive thrombolysis in acute ischemia, and morphology-based risk stratification using intraluminal thrombus volume rather than diameter alone, while sex-specific disparities including a threefold higher amputation risk in symptomatic women highlight an unresolved equity gap. Clinically, these signals suggest that conduit choice, surgical approach, and patient selection remain more influential than modality alone, and that endovascular repair is best reserved for anatomically eligible or high-risk patients under strict surveillance. Given the heterogeneity in diagnostic criteria and the predominance of retrospective evidence, future research should prioritize prospective comparative trials of next-generation hinge-point–tolerant stent-grafts, sex-specific intervention thresholds, and thrombus-volume–guided treatment algorithms to clarify durability and equity of care.

Keywords: Popliteal artery aneurysm; Endovascular repair; Open surgical repair; Stent graft; Vein graft; Acute limb ischemia; Primary patency; Limb salvage; Ruptured popliteal artery aneurysm; Posterior surgical approach

Review Stats

Final search date and database lock: 2026-05-02 20:38:43 CEST
Plan: Pro (expanded craft tokens; source: PubMed)
Source: PubMed
Total Abstracts/Papers: 455
Downloaded Abstracts/Papers: 455
Included original and non-original Abstracts/Papers (all): 209
Included original Abstracts/Papers (Vote counting by direction of effect): 188
Reference Index (links used in paper): 107
Total participants (topic deduplicated ΣN): 29285

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Reference Index (107)

[1] Ruptured popliteal artery aneurysm. — https://doi.org/10.1002/bjs.10953
[2] Results of Surgical Treatment for Popliteal Aneurysm. — https://doi.org/10.1016/j.avsg.2021.09.025
[3] Natural history, growth rates, and treatment of popliteal artery aneurysms. — https://doi.org/10.1016/j.jvs.2021.07.243
[4] Endovascular versus open repair of asymptomatic popliteal artery aneurysm. — https://doi.org/10.1002/14651858.cd010149.pub3
[5] Angiosarcoma masquerading as popliteal artery aneurysm. — https://doi.org/10.1024/0301-1526/a001289
[6] Evolving treatment of popliteal artery aneurysms. — https://doi.org/10.1016/j.jvs.2012.10.122
[7] Late outcomes of Viabahn self-expandable covered stents for the elective treatment of popliteal artery aneurysms. — https://doi.org/10.1016/j.jvs.2025.06.049
[8] Two Decades of Endovascular Repair of Popliteal Artery Aneurysm--A Meta-analysis. — https://doi.org/10.1016/j.ejvs.2015.04.036

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