☸️SAIMSARA Journal
Online First Issues About Impressum

AI-Native Scoping Reviews & Evidence Mapping

ISSN 3054-3991 · ISSN record ↗
The Journal publishes machine-generated scoping reviews in medical and life sciences under human-editorial oversight, with transparent citations and versioning. Online First articles are continuously released by registered users. Issues are organized by domain and linked to an interactive AI RAG chatbot.
Editor's Choice papers are marked with .

Read aims & scope, publishing model & policies →

Issues

Domain issues provide a same-page filtered article view and a paired RAG agent.
Cardiac & Vascular Health icon
Cardiac & Vascular Health
Issue 1 • Vol 1 (2026) in progress
Longevity & Public Health icon
Longevity & Public Health
Issue 2 • Vol 1 (2026) in progress
Digital Health & Biotech icon
Digital Health & Biotech
Issue 3 • Vol 1 (2026) in progress
Mental & Neurological Health icon
Mental & Neurological Health
Issue 4 • Vol 1 (2026) in progress
Sports Medicine icon
Sports Medicine
Issue 5 • Vol 1 (2026) in progress
Pain Medicine icon
Pain Medicine
Issue 6 • Vol 1 (2026) in progress
Infectious Diseases icon
Infectious Diseases
Issue 7 • Vol 1 (2026) in progress
Skin & Aesthetics icon
Skin & Aesthetics
Issue 8 • Vol 1 (2026) in progress
Gastrointestinal & Metabolic Health icon
Gastrointestinal & Metabolic Health
Issue 9 • Vol 1 (2026) in progress
Head and Neck Health icon
Head and Neck Health
Issue 10 • Vol 1 (2026) in progress
To propose a new domain issue or suggest curation criteria, use Impressum contact.
Online First: 225 article(s) • Page 8 / 19 Full archive (source) →
Digital Health & Biotech Digital Health & Biotech
FDA approval is not always the end of uncertainty — this evidence map shows how surrogate endpoints, accelerated pathways, thin pivotal trials, underrepresented populations, and delayed confirmatory evidence can leave major clinical questions unresolved after approval. The full evidence map helps clinicians, researchers, and policy-minded readers distinguish regulatory authorization from proven real-world benefit, safety, equity, and patient-centered value.
Updated: 2026-05-22 • ID: fda-approval-pitfalls-20260517-174500-e25de34b • Editorial check 2026-05-22
Skin & Aesthetics Skin & Aesthetics
Surgical loupes are not just magnifying glasses — they are practical visualization tools for microsurgery, aesthetic precision, reconstruction, dental procedures, and surgeon ergonomics. This evidence map shows where loupes can match microscopes, where they improve workflow, and where advanced visualization remains necessary.
Updated: 2026-05-22 • ID: surgical-loupes-20260517-154729-3d02cfe3 • Editorial check 2026-05-22
Sports Medicine Sports Medicine
This review maps 29 original studies comparing barefoot, minimalist, mobility, and conventional footwear across gait biomechanics, foot morphology, stability, knee loading, and performance. It shows where barefoot-like footwear may be useful — fall-risk stability, intrinsic foot strength, and knee OA load reduction — and where conventional shoes still matter, especially for impact moderation and postoperative walking capacity.
Updated: 2026-05-22 • ID: barefoot-conventional-shoes-20260429-204053-8b5ecae1 • Editorial check 2026-05-22
Mental & Neurological Health Mental & Neurological Health
Neuroleptic side effects are not only an EPS problem: the evidence map shows how motor toxicity, metabolic burden, endocrine disruption, sedation, autonomic effects, and patient-reported distress shift across drug classes and vulnerable populations. The full evidence map helps clinicians and researchers see where antipsychotics reduce risk, where they simply move toxicity into another domain, and why structured side-effect monitoring is essential in real-world care.
Updated: 2026-05-22 • ID: side-effects-neuroleptics-20260516-233742-690dd0a7 • Editorial check 2026-05-22
Digital Health & Biotech Digital Health & Biotech
AI can already imitate parts of executive work — drafting CEO-style messages, supporting decisions, and simulating crisis responses — but the evidence shows that authority, trust, ethics, and accountability still remain deeply human problems. The full SAIMSARA evidence map reveals where AI may genuinely augment leadership, where it becomes symbolic hype, and why the future CEO is more likely to be human-with-AI than AI-alone.
Updated: 2026-05-21 • ID: ai-ceo-20260516-202454-72fed8ad • Editorial check 2026-05-21
Pain Medicine Pain Medicine
Spinal cord stimulation is not simply an implant for chronic pain — it is a long-term neuromodulation pathway where benefit depends on careful selection, anatomy-aware implantation, psychosocial screening, and active device management. The full paper maps 270 references across 631 original studies to show where SCS is strongest, where complications cluster, and which patients may gain durable value rather than repeated revision or explantation.
Updated: 2026-05-21 • ID: spinal-cord-stimulator-20260515-234426-8a90f9b4 • Editorial check 2026-05-21
Cardiac & Vascular Health Cardiac & Vascular Health
Vascular closure devices are not simply tools to close a puncture site — they are workflow-enabling technologies whose value depends on anatomy, sheath size, imaging guidance, device selection, and bailout readiness. The full evidence map shows where VCDs accelerate hemostasis, ambulation, and discharge, and where complications cluster across femoral, large-bore, venous, TAVR, EVAR, ECMO, PCI, and electrophysiology settings.
Updated: 2026-05-21 • ID: vascular-closure-device-20260516-195936-7e1ad38d • Editorial check 2026-05-21
Cardiac & Vascular Health Cardiac & Vascular Health
Impella is not a simple “more support means better outcome” device: across 194 references and 432 original studies, the evidence shows a constant trade-off between ventricular unloading, survival signals, and complications such as bleeding, hemolysis, thrombocytopenia, vascular injury, and acquired von Willebrand syndrome. The full ☸️SAIMSARA evidence map shows where Impella appears strongest — early AMI-cardiogenic shock support, high-risk PCI, bridge-to-transplant/LVAD pathways, and selected RV failure scenarios — and where the evidence remains fragile, observational, or safety-limited.
Updated: 2026-05-20 • ID: impella-device-20260515-184929-7f98a528
Mental & Neurological Health Mental & Neurological Health
Alcohol and depression are not a simple “alcohol causes depression” story: across 185 references and 3,711 original studies, the evidence separates moderate-use signals from the consistent harms of heavy drinking, AUD, coping-motivated use, suicidality, relapse, and mortality. The full ☸️SAIMSARA evidence map gives a reference-linked view of where causality remains uncertain, which mechanisms matter clinically, and why integrated screening and treatment are needed instead of treating alcohol and depression as separate problems.
Updated: 2026-05-20 • ID: alcohol-depression-20260515-184039-2d680d6d
Digital Health & Biotech Digital Health & Biotech
Electronic health records are not won by one “best” vendor: the evidence shows that usability, clinical decision support, interoperability, analytics readiness, workflow fit, and governance decide whether an EHR actually improves care. Built from 57 references and 130 original studies, the full ☸️SAIMSARA evidence map gives a practical, reference-linked view of what makes EHR systems work — and where they fail in real clinical settings.
Updated: 2026-05-20 • ID: best-ehr-system-20260515-175218-40f2f857
Cardiac & Vascular Health Cardiac & Vascular Health
Behçet’s disease is far more than recurrent mouth ulcers: this evidence map shows it as a whole-body inflammatory vasculitis that can threaten vision, veins, arteries, brain, gut, and quality of life. The full review explains which diagnostic signals, genetic mimics, and modern therapies — especially anti-TNF agents, apremilast, colchicine, and emerging JAK inhibitors — may change how Behçet’s disease is recognized and treated.
Updated: 2026-05-20 • ID: behcet-disease-20260503-084409-c6b709d7 • Editorial check 2026-05-20
Skin & Aesthetics Skin & Aesthetics
Cosmetic botulinum toxin is not just “wrinkle treatment”: this evidence map shows where it works, where technique and anatomy decide outcomes, and where real safety risks emerge from unregulated products, poor training, or weak counseling. Built from 201 references and 304 original studies, the full map gives a practical, reference-linked view of efficacy, complications, patient satisfaction, technique choices, and regulatory gaps for modern aesthetic practice.
Updated: 2026-05-20 • ID: botulinum-toxin-cosmetic-20260515-054330-25ad2129 • Editorial check 2026-05-20
© 2026 SAIMSARA Journal • Impressum • Published by ML in Health Science GbR