AI-Native Scoping Reviews & Evidence Mapping

This review maps a large clinical evidence base showing that COVID-19 vaccines were generally linked to a strong safety-benefit balance: serious complications such as myocarditis and VITT were rare, while protection against severe COVID-19 outcomes and death remained substantial. Read the full paper to see which risks were truly recurrent, which populations were most vulnerable, and how the balance differed by vaccine platform, age, pregnancy, chronic disease, and immunocompromised status.

AI cybercrime is no longer just a technical threat but a dual-use arms race: the same AI systems that scale phishing, deepfakes, fraud, and offender automation are also powering detection, forensic triage, and evidence preservation. This full evidence map shows where the strongest signals actually lie — from high-accuracy phishing and fraud detection to blockchain-backed forensics, XAI, governance gaps, and the unresolved question of whether AI-generated evidence can be trusted in real legal workflows.

AI chatbots are becoming more than tools: this evidence map shows how loneliness, perceived empathy, parasocial bonding, and satisfaction can turn conversational support into emotional dependency, over-reliance, and withdrawal-like patterns. The full review separates original evidence from opinion literature and maps where the strongest signals emerge across attachment, social disconnection, Replika-style companion use, student dependency, and design strategies to reduce harm.

EMA approval is not the end of evidence generation, but the start of a lifecycle in which uncertainty must be resolved through post-authorization studies, pharmacovigilance, RWE, and reimbursement reassessment. This evidence map shows where regulatory access, conditional authorization, surrogate endpoints, safety monitoring, and real-world confirmation succeed — and where they still leave clinicians, payers, and patients with critical unanswered questions.

FDA approval is not always the end of uncertainty — this evidence map shows how surrogate endpoints, accelerated pathways, thin pivotal trials, underrepresented populations, and delayed confirmatory evidence can leave major clinical questions unresolved after approval. The full evidence map helps clinicians, researchers, and policy-minded readers distinguish regulatory authorization from proven real-world benefit, safety, equity, and patient-centered value.

Surgical loupes are not just magnifying glasses — they are practical visualization tools for microsurgery, aesthetic precision, reconstruction, dental procedures, and surgeon ergonomics. This evidence map shows where loupes can match microscopes, where they improve workflow, and where advanced visualization remains necessary.

This review maps 29 original studies comparing barefoot, minimalist, mobility, and conventional footwear across gait biomechanics, foot morphology, stability, knee loading, and performance. It shows where barefoot-like footwear may be useful — fall-risk stability, intrinsic foot strength, and knee OA load reduction — and where conventional shoes still matter, especially for impact moderation and postoperative walking capacity.